Specimen Name Result Units Range

Plasma Sodium 137 mmol/L (135-145)
Potassium 4.2 mmol/L (3.5-5.5)
Chloride 102 mmol/L (100-109)
Bicarbonate 27 mmol/L (22-32)
Anion Gap 12 mmol/L (7-17)
Glucose 6.2 mmol/L (3.8-5.5)
Urea 5.4 mmol/L (2.7-7.2)
Creatinine 97 μmol/L (60-110)
Phosphate 1.20 mmol/L (0.80-1.45)
Total Calcium 2.23 mmol/L (2.10-2.55)
Albumin 46 g/L (34-48)
Total Protein 72 g/L (60-80)
Total Bilirubin 42 μmol/L (6-24)
GGT 24 U/L (< 60)
ALP 75 U/L (30-110)
ALT 30 U/L (< 55)
AST 35 U/L (< 45)

Otherwise healthy 24yo male following elective surgery.


Gilbert's Syndrome
  • mild (unconjugated) hyperbilirubinaemia
  • normal LTFs
  • no bilirubinuria
  • no haemolysis

 

Post-Operative Jaundice

  1. pre-hepatic
    • transfusion related
      • free-Hb, incompatability, mechanical damage
      • old / out-of-date, incorrectly stored blood
    • resorption of haematoma
  2. hepatic
    • congenital
      • Gilbert's (ligandin deficiency → ↓uptake)
      • Crigler-Najjar (Type 2 - ↓glucuronyl-transferase)
      • Rotor and Dubin-Johnson (↓ biliary excretion)
    • drug-induced
      • halothane, enflurane
      • flucloxacillin, rifampicin, isoniazid
      • methyl-dopa, paracetamol
    • infective hepatitis, septicaemia
    • hypovolaemia, hypotension, hypoxia
    • hepatic ischaemia/hypoxia
    • toxins
    • trauma
  3. post-hepatic
    • bile duct trauma, oedema, ligation
    • cholangitis
    • cholelithiasis, stones
    • pancreatic / ductal carcinoma