Specimen Name Result Units Range
Blood Hb 230 g/L (130-180)
     R.B.C. 7.9 x1012/L (4.5-6.0)
     P.C.V. 0.59 L/L (0.4-0.5)
     M.C.V. 75 fL (80-98)
     M.C.H.C. 338 g/L (315-355)
Platelets 1,100 x109/L (150-450)
WCC 14.4 x109/L (4.0-11.0)
     Neutrophils 11.1  (77) x109/L  (%) (1.8-7.5)
     Lymphocytes 2.60  (18) x109/L  (%) (1.0-3.5)
     Monocytes 0.30  (2.1) x109/L  (%) (0.2-0.8)
     Eosinophils 0.10  (0.69) x109/L  (%) (< 0.5)
     Basophils 0.20  (1.4) x109/L  (%) (< 0.1)
     Bands 0.10  (0.69) x109/L  (%) (0.2-0.4)

Film: Red blood cells show microcytosis and slight anisocytosis. Occasional myelocytes and metamyelocytes.

66yo female.
Polycythaemia rubra vera
  • polycythaemia →
    • PCV > 52% 180 g/L males
    • PCV > 47% 165 g/L females
  • ↑RBC mass with ↑WBC's and platelets ≈ 50%
  • pruritis, plethoric facies, retinal vein engorgement
  • symptoms of impaired cerebral blood flow
  • accelerated atherosclerotisis
  • thrombotic, or haemorrhagic disease
  • splenomegaly ≈ 75% ± hepatomegaly
  • survival ≈ 2 yrs without Rx → ≈ 10-12 years with,
  • Rx : phlebotomy, myelosuppressive therapy (DXRT, hydroxyurea)