Specimen Name Result Units Range
Blood Hb 97 g/L (130-180)
     R.B.C. 3.2 x1012/L (4.5-6.0)
     P.C.V. 0.30 L/L (0.4-0.5)
Platelets 1,083 x109/L (150-450)
WCC 25.8 x109/L (4.0-11.0)
     Neutrophils 19.4  (75) x109/L  (%) (1.8-7.5)
     Monocytes 1.29  (5.0) x109/L  (%) (0.2-0.8)
     Myelocytes 2.06  (8.0) x109/L  (%) (< 0.1)
     Metamyelocytes 1.03  (4.0) x109/L  (%) (< 0.5)
     Nucleated rbc 2 / 100 WBC (0)

Film Review: Moderate anisocytosis. Slight polychromasia. Increased rouleaux formation. Leukoerythroblastic blood picture. Leucocytosis. Marked thrombocytosis.
Query - reactive. Suggest repeat blood film in one week.

56yo female with mailaise, weight-loss and night sweats.
Leucoerythroblastic Blood Picture
  • anaemia with nucleated rbc's
  • leukocytosis with immature wbc precursors
  • blood films : Film1, Film2

 

Aetiology:

  1. bone marrow infiltration
    • metastatic carcinoma
    • multiple myeloma, leukaemia, lymphoma
    • myelofibrosis
    • histiocytosis
    • miliary tuberculosis
    • osteopetrosis
  2. 'stressed' marrow
    • ↓DO2 - severe haemolysis / anaemia / hypoxaemia
    • severe burns